{"id":7842,"date":"2023-05-22T13:44:06","date_gmt":"2023-05-22T11:44:06","guid":{"rendered":"https:\/\/efvr1v90ll.wpdns.site\/bez-katehorii\/celsis-luminometers\/"},"modified":"2023-06-29T15:59:10","modified_gmt":"2023-06-29T12:59:10","slug":"celsis-luminometers","status":"publish","type":"post","link":"https:\/\/alsi.ua\/en\/rapid-microbiological-detection-systems\/celsis-luminometers\/","title":{"rendered":"Celsis\u00ae luminometers"},"content":{"rendered":"<p><strong>Celsis\u00ae Rapid Microbiological Detection <\/strong><strong>Systems<\/strong> use a patented technology to enhance the bioluminescence of ATP molecules, which allows testing of product sterility within 4-6 days and microbiological purity within 24 hours. The speed of results and reliability of <strong>Celsis\u00ae luminometers<\/strong> far exceed the capabilities of traditional methods.<\/p>\n<p>The <strong>AMPiScreen\u00ae<\/strong> reagent technology provides faster turnaround times than its competitors and is capable of detecting ultra-low levels of microbial contamination by utilizing a series of enzymatic reactions to detect even the lowest concentrations of microbial ATP. <strong>AMPiScreen\u00ae<\/strong> delivers results up to 50% faster than standard ATP bioluminescence by significantly reducing the incubation period.<\/p>\n<p><strong>Celsis\u00ae<\/strong> <strong>systems<\/strong> are designed to meet the need for fast time-to-market. Timely notification of microbiological contamination allows you to quickly streamline laboratory processes and reduce financial costs.<\/p>\n<div class=\"video-shortcode\"><iframe title=\"Celsis\u00ae: A Comprehensive Solution for Rapid Microbial Detection\" width=\"1260\" height=\"709\" src=\"https:\/\/www.youtube.com\/embed\/b9f8B_jSql8?feature=oembed\" frameborder=\"0\" allow=\"accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture; web-share\" allowfullscreen><\/iframe><\/div>\n<p>To the series  <strong>Celsis\u00ae rapid microbiological detection systems<\/strong>  offers two models of luminometers: a compact system  <strong>Celsis Accel\u00ae<\/strong>which provides a productivity of up to 30 analyzes per hour and is designed for laboratories with small volumes of product analysis, and the innovative  <strong>Celsis Advance II\u00ae,<\/strong>  is designed for large production capacities and allows for the analysis of up to 120 samples per hour.<\/p>\n<table style=\"width: 100%;\" width=\"100%\">\n<tbody>\n<tr style=\"background-color: #96c8e7;\">\n<td style=\"border-style: solid;\" width=\"189\"><\/td>\n<td style=\"border-style: solid; text-align: center;\" width=\"307\"><a href=\"https:\/\/alsi.ua\/product\/obladnannia\/systemy-shvydkoi-mikrobiolohichnoi-detektsii\/systemy-shvydkoi-mikrobiolohichnoi-detektsii-selsis\/liuminometr-celsis-accel\/\"><strong>Celsis\u00ae<\/strong><strong> Accel<\/strong><strong>system<\/strong><\/a><\/td>\n<td style=\"border-style: solid; text-align: center;\" width=\"351\"><a href=\"https:\/\/alsi.ua\/product\/obladnannia\/systemy-shvydkoi-mikrobiolohichnoi-detektsii\/systemy-shvydkoi-mikrobiolohichnoi-detektsii-selsis\/liuminometr-celsis-advance-ii\/\"><strong>Celsis\u00ae<\/strong><strong> Advance II<\/strong><strong>system<\/strong><\/a><\/td>\n<\/tr>\n<tr>\n<td style=\"border-style: solid;\" width=\"189\"><strong>Designed for<\/strong><\/td>\n<td style=\"border-style: solid;\" width=\"307\">microbiological quality control laboratories of enterprises with medium and small production capacities<\/td>\n<td style=\"border-style: solid;\" width=\"351\">microbiological quality control laboratories of enterprises with large production capacities<\/td>\n<\/tr>\n<tr>\n<td style=\"border-style: solid;\" width=\"189\"><strong>Productivity<\/strong><\/td>\n<td style=\"border-style: solid;\" width=\"307\">30 samples per hour with the ability to combine multiple batches into one run<\/td>\n<td style=\"border-style: solid;\" width=\"351\">120 samples per hour with the ability to combine multiple batches into one run<\/td>\n<\/tr>\n<tr>\n<td style=\"border-style: solid;\" width=\"189\"><strong>Dimensions<\/strong><\/td>\n<td style=\"border-style: solid;\" width=\"307\">33 cm x 37 cm x 52 cm (WxHxD)<\/td>\n<td style=\"border-style: solid;\" width=\"351\">65.6 cm x 40.1 cm x 43.3 cm (WxHxD)<\/td>\n<\/tr>\n<tr>\n<td style=\"border-style: solid;\" width=\"189\"><strong>Weight<\/strong><\/td>\n<td style=\"border-style: solid;\" width=\"307\">24 kg<\/td>\n<td style=\"border-style: solid;\" width=\"351\">28 kg<\/td>\n<\/tr>\n<tr>\n<td style=\"border-style: solid;\" width=\"189\"><strong>Electrical specifications<\/strong><\/td>\n<td style=\"border-style: solid;\" width=\"307\">100-240 V, 50\/60 Hz<\/td>\n<td style=\"border-style: solid;\" width=\"351\">100-240 V, 50\/60 Hz<\/td>\n<\/tr>\n<tr>\n<td style=\"border-style: solid;\" width=\"189\"><strong>Article no.<\/strong><\/td>\n<td style=\"border-style: solid;\" width=\"307\">7460288<\/td>\n<td style=\"border-style: solid;\" width=\"351\">7456004<\/td>\n<\/tr>\n<tr>\n<td style=\"border-style: solid;\"><strong> <\/strong><\/td>\n<td style=\"border-style: solid;\"><a href=\"https:\/\/alsi.ua\/product\/obladnannia\/systemy-shvydkoi-mikrobiolohichnoi-detektsii\/systemy-shvydkoi-mikrobiolohichnoi-detektsii-selsis\/liuminometr-celsis-accel\/\"><img decoding=\"async\" class=\"lazyload size-medium wp-image-4260 aligncenter\" src=\"https:\/\/alsi.ua\/wp-content\/uploads\/2022\/06\/Celsis-Accel-1-300x148.png\" data-orig-src=\"https:\/\/alsi.ua\/wp-content\/uploads\/2022\/06\/Celsis-Accel-1-300x148.png\" alt=\"\" width=\"300\" height=\"148\" srcset=\"data:image\/svg+xml,%3Csvg%20xmlns%3D%27http%3A%2F%2Fwww.w3.org%2F2000%2Fsvg%27%20width%3D%27300%27%20height%3D%27148%27%20viewBox%3D%270%200%20300%20148%27%3E%3Crect%20width%3D%27300%27%20height%3D%27148%27%20fill-opacity%3D%220%22%2F%3E%3C%2Fsvg%3E\" data-srcset=\"https:\/\/alsi.ua\/wp-content\/uploads\/2022\/06\/Celsis-Accel-1-200x99.png 200w, https:\/\/alsi.ua\/wp-content\/uploads\/2022\/06\/Celsis-Accel-1-300x148.png 300w, https:\/\/alsi.ua\/wp-content\/uploads\/2022\/06\/Celsis-Accel-1-400x198.png 400w, https:\/\/alsi.ua\/wp-content\/uploads\/2022\/06\/Celsis-Accel-1-500x247.png 500w, https:\/\/alsi.ua\/wp-content\/uploads\/2022\/06\/Celsis-Accel-1-600x297.png 600w, https:\/\/alsi.ua\/wp-content\/uploads\/2022\/06\/Celsis-Accel-1-700x346.png 700w, https:\/\/alsi.ua\/wp-content\/uploads\/2022\/06\/Celsis-Accel-1-768x380.png 768w, https:\/\/alsi.ua\/wp-content\/uploads\/2022\/06\/Celsis-Accel-1-800x395.png 800w, https:\/\/alsi.ua\/wp-content\/uploads\/2022\/06\/Celsis-Accel-1-1024x506.png 1024w, https:\/\/alsi.ua\/wp-content\/uploads\/2022\/06\/Celsis-Accel-1-1200x593.png 1200w, https:\/\/alsi.ua\/wp-content\/uploads\/2022\/06\/Celsis-Accel-1-1536x759.png 1536w\" data-sizes=\"auto\" data-orig-sizes=\"(max-width: 300px) 100vw, 300px\" \/><\/a><\/td>\n<td style=\"border-style: solid;\"><a href=\"https:\/\/alsi.ua\/product\/obladnannia\/systemy-shvydkoi-mikrobiolohichnoi-detektsii\/systemy-shvydkoi-mikrobiolohichnoi-detektsii-selsis\/liuminometr-celsis-advance-ii\/\"><img decoding=\"async\" class=\"lazyload size-medium wp-image-4261 aligncenter\" src=\"https:\/\/alsi.ua\/wp-content\/uploads\/2022\/06\/Celsis-Advance-II-1-300x198.png\" data-orig-src=\"https:\/\/alsi.ua\/wp-content\/uploads\/2022\/06\/Celsis-Advance-II-1-300x198.png\" alt=\"\" width=\"300\" height=\"198\" srcset=\"data:image\/svg+xml,%3Csvg%20xmlns%3D%27http%3A%2F%2Fwww.w3.org%2F2000%2Fsvg%27%20width%3D%27300%27%20height%3D%27198%27%20viewBox%3D%270%200%20300%20198%27%3E%3Crect%20width%3D%27300%27%20height%3D%27198%27%20fill-opacity%3D%220%22%2F%3E%3C%2Fsvg%3E\" data-srcset=\"https:\/\/alsi.ua\/wp-content\/uploads\/2022\/06\/Celsis-Advance-II-1-200x132.png 200w, https:\/\/alsi.ua\/wp-content\/uploads\/2022\/06\/Celsis-Advance-II-1-300x198.png 300w, https:\/\/alsi.ua\/wp-content\/uploads\/2022\/06\/Celsis-Advance-II-1-400x264.png 400w, https:\/\/alsi.ua\/wp-content\/uploads\/2022\/06\/Celsis-Advance-II-1-500x330.png 500w, https:\/\/alsi.ua\/wp-content\/uploads\/2022\/06\/Celsis-Advance-II-1-600x396.png 600w, https:\/\/alsi.ua\/wp-content\/uploads\/2022\/06\/Celsis-Advance-II-1-700x461.png 700w, https:\/\/alsi.ua\/wp-content\/uploads\/2022\/06\/Celsis-Advance-II-1-768x506.png 768w, https:\/\/alsi.ua\/wp-content\/uploads\/2022\/06\/Celsis-Advance-II-1-800x527.png 800w, https:\/\/alsi.ua\/wp-content\/uploads\/2022\/06\/Celsis-Advance-II-1-1024x675.png 1024w, https:\/\/alsi.ua\/wp-content\/uploads\/2022\/06\/Celsis-Advance-II-1-1200x791.png 1200w, https:\/\/alsi.ua\/wp-content\/uploads\/2022\/06\/Celsis-Advance-II-1-1536x1012.png 1536w\" data-sizes=\"auto\" data-orig-sizes=\"(max-width: 300px) 100vw, 300px\" \/><\/a><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p><strong>Validation of an alternative method for determining sterility of Celsis AMPiScreen\u00ae<\/strong><\/p>\n<p>Validation of a rapid microbiological detection method requires extensive planning, documentation, testing, validation, and validation of method data, which typically takes several months to several years. This is the reason why rapid microbiological detection is often an obstacle to the implementation of rapid microbiological detection in the pharmaceutical and biotechnology industries. In addition, a thorough understanding of microbiology, statistics, and regulatory requirements is required to validate a sterility method. While validation is crucial, it should not be a barrier to successful implementation and reaping the benefits of an alternative method.<\/p>\n<p>To meet the requirements for effective and reliable validation of rapid microbiological detection, Celsis\u00ae has developed the Celsis\u00ae Complete sterility validation and reporting package, which includes an equivalence report in combination with methods for testing method stability and reliability, detection limit, and product specificity. The Celsis\u00ae Validation Package reduces the number of resource-intensive steps in the validation of an alternative method, reducing the total validation time to a few months.<\/p>\n<table style=\"width: 95.1364%;\">\n<tbody>\n<tr>\n<td style=\"border-style: solid; width: 76.8817%;\" width=\"425\">Celsis\u00ae Complete &#8211; Validation package for the Celsis\u00ae membrane filtration sterility method<\/td>\n<td style=\"border-style: solid; width: 91.3978%;\" width=\"118\">VAL6000MF<\/td>\n<\/tr>\n<tr>\n<td style=\"border-style: solid; width: 76.8817%;\" width=\"425\">Celsis\u00ae Advantage &#8211; Protocol for the Celsis\u00ae Sterility Determination Method by Membrane Filtration<\/td>\n<td style=\"border-style: solid; width: 91.3978%;\" width=\"118\">VAL6100MF<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p><a href=\"https:\/\/alsi.ua\/accountant-home\/partnery\/#CRL\"><br \/>\n  <strong>Charles River\u00ae.<\/strong><br \/>\n<\/a> provides a rapid implementation of an alternative method for determining sterility with a complete equivalence report of Celsis\u00ae Rapid Microbiological Detection, based on Celsis AMPiScreen\u00ae ATP Amplified Bioluminescence Technology, prior to membrane filtration sterility testing. The equivalence report reduces the validation time to 3-6 months by eliminating the need to confirm the equivalence of an alternative method and allowing the validation team to proceed immediately to the method validation parameters.<\/p>\n<p>The report demonstrates the equivalence of the Celsis AMPiScreen\u00ae rapid microbiological detection method with a 6-day incubation to the classical sterility testing method with a 14-day incubation for qualitative screening of pharmaceutical products for microbial contamination in accordance with USP &lt;71&gt;, Ph. Eur 2.6.1 and JP 4.06.<\/p>\n<table style=\"width: 95.3376%;\">\n<tbody>\n<tr>\n<td style=\"border-style: solid; width: 76.8817%;\" width=\"425\">Celsis\u00ae equivalence report to the membrane filtration sterility test method<\/td>\n<td style=\"border-style: solid; width: 91.7563%;\" width=\"118\">VAL4000EQ<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n","protected":false},"excerpt":{"rendered":"<p>Celsis\u00ae Rapid Microbiological Detection Systems use a patented technology to [&hellip;]<\/p>\n","protected":false},"author":10,"featured_media":7619,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"inline_featured_image":false,"footnotes":""},"categories":[875],"tags":[],"class_list":["post-7842","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-rapid-microbiological-detection-systems"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.7 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Celsis\u00ae luminometers &#8226; 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